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Significant advances in cancer treatment

Scientists in the UK announced that the results of a new cancer treatment that kills cancerous cells are very promising.

A new type of cancer treatment that kills cancerous cells by acting on them has shown promising results in first human trials.

According to the BBC Turkish news, scientists from England reported that while all cancerous cells of a cancer patient were destroyed, the cancerous tumors of the others shrank. The virus is an attenuated form of herpes virus; it was played on this form in a way that it would kill tumors.

Longer and larger studies are needed to see if the treatment really works. But the BBC’s health editor, Michelle Roberts, says that even at this stage, experts say that if viruses are injected into cancer patients, there may be hope of recovery even for patients with advanced cancer.

The research is being led by the Cancer Research Institute at the Royal Marsden Foundation of England’s National Health Service (NHS).

NEEDLES ARE MADE DIRECTLY TO THE TUMOR

Krzysztof Wojkowski, 39, who lives in west London, is one of the patients participating in the ongoing phase of the study. Wojkowski, who was diagnosed with cancer of the salivary glands in the mouth area in 2017, could not defeat the cancer despite undergoing many surgeries and treatments. On the contrary, the disease progressed further.

“I was told that I had no other choice, now I was in intensive care. It was a very devastating situation, so it was an incredible situation to be given the chance to participate in this study,” said Wojkowski.

Wojkowski said, “I got an injection every two weeks, for a total of five weeks. It has been two years now and there are no cancerous cells in my body anymore,” he said.

Injections made directly into the tumor attack the cancerous cells in two ways: It surrounds and detonates the cancerous cells; Then it activates the immune system. In studies involving about 40 patients, some patients were directly injected with this modified herpes virus called RP2, a cold virus that normally causes herpes. Other patients continued to be given the cancer drugs they had taken with these injections.

According to the results obtained;

Three out of nine patients who were given RP2 alone – one of them Wojkowski – found tumors shrunk

– Treatment gave positive results in seven of 30 patients who continued to take cancer medication

-Side effects such as fatigue felt very mildly

‘RESULTS ARE VERY IMPRESSIVE’

The head of the research team, Prof. Kevin Harrington told the BBC that the results of his treatment were “really impressive”, noting that he has also treated some advanced cancers:

“It’s rare to see such positive results at this early stage of clinical research, in this first step towards testing the safety of the treatment. We have also obtained positive results in patients whose treatment has been terminated. I look forward to seeing if we will continue to get positive results as the number of patients participating in the study increases.”

This isn’t actually the first time scientists have used viruses to fight cancer. A few years ago, the NHS had approved a cold virus-based treatment for advanced skin cancer, called T-Vec.

prof. Harrington says the RP2 is an enhanced version of T-Vec. From Cancer Research UK, Dr. Marianne Baker also states that even the current results could make big changes in cancer treatment:

“Scientists discovered nearly 100 years ago that viruses could work in the treatment of cancer. But implementing it safely and effectively has proven very difficult. This new virus therapy shows promise in its infancy, now we need more studies to be done and see how the treatment works. “Studies show that combining multiple therapies is a powerful strategy, and virus therapy may play an important role in that strategy.”

Source From: Sozcu

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